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What Is Compazine® (Prochlorperazine) Used compazine For? Tardive DyskinesiaAs with all antipsychotic agents, tardive dyskinesia may appear in some patients on lengthy-time period therapy or may appear after drug therapy has been discontinued. The syndrome also can develop, though a lot less frequently, after relatively brief compazine treatment intervals at low doses. The symptoms are persistent and in some sufferers appear to be irreversible. Sometimes these may be accompanied by involuntary movements of extremities. In uncommon situations, these involuntary movements of the extremities are the only manifestations of tardive dyskinesia. The syndrome may remit, partially or fully, if therapy is discontinued.The effect that symptomatic suppression has upon the lengthy-time period course of the syndrome is unknown.Phenothiazines may suppress the indicators and signs of the syndrome and thereby might possibly mask the underlying course of.The want for compazine continued therapy ought to be reassessed periodically.Given these considerations, prochlorperazine must be prescribed in a way that's more than likely to attenuate the occurrence of tardive dyskinesia. compazine compazine compazine Compazine 500mg side effects. Elderly patients with dementia-related psychosis handled with antipsychotic medication are at an increased risk of death. Analyses of seventeen placebo-controlled trials , largely in sufferers taking atypical antipsychotic medication, revealed a danger of death in drug-handled sufferers of between 1.6 to 1.7 times the risk of demise in placebo-handled sufferers. Over the course of a typical 10-week controlled trial, the speed of dying in drug-treated sufferers was about four.5%, com- pared to a rate of about 2.6% within the placebo group. Observational research recommend that, much like atypical antipsychotic medication, remedy with conventional antipsychotic drugs might enhance mortality. The extent to which the findings of elevated mortality in observational research may be attributed to the antipsychotic drug as opposed to some attribute of the patients is not clear.
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